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Article

Polycystin-2 is an intracellular calcium release channel.

Nature cell biology - 1 Mar 2002

Koulen Peter, Cai Yiqiang, Geng Lin, Maeda Yoshiko, Nishimura Sayoko, Witzgall Ralph, Ehrlich Barbara E, Somlo Stefan

Abstract excerpt

Polycystin-2, the product of the gene mutated in type 2 autosomal dominant polycystic kidney disease (ADPKD), is the prototypical member of a subfamily of the transient receptor potential (TRP) channel superfamily, which is expressed abundantly in the endoplasmic reticulum (ER) membrane. Here, we...

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Source

Identifiers

PMID: 11854751
DOI: 10.1038/ncb754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11854751-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Polycystin-2 is an intracellular calcium release channel.PMID 11854751Read ↗

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