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Article

Distinct mechanisms of clathrin-independent endocytosis have unique sphingolipid requirements.

Molecular biology of the cell - 1 Jul 2006

Cheng Zhi-Jie, Singh Raman Deep, Sharma Deepak K, Holicky Eileen L, Hanada Kentaro, Marks David L, Pagano Richard E

Abstract excerpt

Sphingolipids (SLs) play important roles in membrane structure and cell function. Here, we examine the SL requirements of various endocytic mechanisms using a mutant cell line and pharmacological inhibitors to disrupt SL biosynthesis. First, we demonstrated that in Chinese hamster ovary cells we could distinguish three distinct mechanisms of clathrin-independent endocytosis (caveolar, RhoA, and Cdc42 dependent)...

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Identifiers

PMID: 16672382
DOI: 10.1091/mbc.e05-12-1101
PMCID: PMC1552047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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