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Article

CYP4A11 polymorphism correlates with coronary endothelial dysfunction in patients with coronary artery disease--the ENCORE Trials.

Atherosclerosis - 1 Dec 2009

Hermann M, Hellermann J P, Quitzau K, Hoffmann M M, Gasser T, Meinertz T, Münzel T, Fleming I, Lüscher T F

Abstract excerpt

BACKGROUND: Cytochrome P450 (CYP) is expressed in the human endothelium and metabolizes arachidonic acid into vasoactive epoxyeicosatrienoic and 20-hydroxyeicosatetraenoic acids. CYP enzymes have been linked to hypertension and generation of reactive oxygen species. Thus, we investigated the impact of several CYP polymorphisms on coronary endothelial function in patients with coronary artery disease (CAD)....

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Source

Identifiers

PMID: 19615687
DOI: 10.1016/j.atherosclerosis.2009.06.009

Genes

CAD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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