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Article

Cyclin-dependent Kinase 5: Novel role of gene variants identified in ADHD.

Scientific reports - 28 Jul 2017

Maitra Subhamita, Chatterjee Mahasweta, Sinha Swagata, Mukhopadhyay Kanchan

Abstract excerpt

Cortical neuronal migration and formation of filamentous actin cytoskeleton, needed for development, normal cell growth and differentiation, are regulated by the cyclin-dependent kinase 5 (Cdk5). Attention deficit hyperactivity disorder (ADHD) is associated with delayed maturation of the brain and hence we hypothesized that cdk5 may have a role in ADHD. Eight functional CDK5 gene variants were analyzed in 848...

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Identifiers

PMID: 28754891
DOI: 10.1038/s41598-017-06852-2
PMCID: PMC5533779

Genes

CDK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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