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Article

Cyclin-dependent kinase 5 is associated with risk for Alzheimer's disease in a Dutch population-based study.

Journal of neurology - 1 May 2008

Arias-Vásquez Alejandro, Aulchenko Yurii S, Isaacs Aaron, van Oosterhout Andy, Sleegers Kristels, Hofman Albert, van Broeckhoven Christine, Oostra Ben A, Breteler Monique, van Duijn Cornelia M

Abstract excerpt

Although the role of the Cdk5 protein in Alzheimer's disease (AD) is well recognized, there have been relatively few studies investigating genetic variants in the CDK5 gene in AD. In this study, we assessed the association between five previously described single nucleotide polymorphisms (SNPs) in the CDK5 gene and late onset AD by means of logistic regression and haplotype association analyses. Including all...

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Source

Identifiers

PMID: 18350355
DOI: 10.1007/s00415-008-0770-5

Genes

CDK5
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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