Article
The d3/fl-GH receptor gene polymorphism does not influence quality of life and body composition in GH-deficient adults receiving GH replacement therapy.
European journal of endocrinology - 1 Oct 2009
Adetunji O R, MacFarlane I A, Javadpour M, Alfirevic A, Pirmohamed M, Blair J C
Abstract excerpt
CONTEXT: The growth response to recombinant human growth hormone (rhGH) in GH deficient (GHD) patients may be influenced by polymorphisms in the growth hormone receptor (GHR) gene. OBJECTIVES: To investigate adults with GHD who have been treated with rhGH for more than 1 year to determine the relationship between genomic deletion of exon 3 in the GHR gene and quality of life (QoL), body composition (BC) and serum...
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