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Article

Influence of the exon 3 deletion of GH receptor and IGF-I level at diagnosis on the efficacy and safety of treatment with somatotropin in adults with GH deficiency.

Pituitary - 1 Feb 2015

Andujar-Plata P, Fernandez-Rodriguez E, Quinteiro C, Casanueva F F, Bernabeu I

Abstract excerpt

PURPOSE: The treatment of adults with GH deficiency (GHD) with human recombinant growth hormone has interindividual variability and several factors influence it. The aims of this study were : 1-to analyze the GH receptor (GHR) genotype in terms of exon 3 deletion GHR (d3-GHR) in adults with GHD; 2-to assess the effects of d3-GHR on initial IGF-I levels; 3-to evaluate whether d3-GHR and/or initial IGF-I levels...

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Source

Identifiers

PMID: 24710993
DOI: 10.1007/s11102-014-0562-0

Genes

GHR

Provenance

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Influence of the exon 3 deletion of GH receptor and IGF-I level at diagnosis on the efficacy and safety of treatment with somatotropin in adults with GH deficiency.PMID 24710993Read ↗

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