Article
The NK-2 class homeodomain factor CEH-51 and the T-box factor TBX-35 have overlapping function in C. elegans mesoderm development.
Development (Cambridge, England) - 1 Aug 2009
Broitman-Maduro Gina, Owraghi Melissa, Hung Wendy W K, Kuntz Steven, Sternberg Paul W, Maduro Morris F
Abstract excerpt
The C. elegans MS blastomere, born at the 7-cell stage of embryogenesis, generates primarily mesodermal cell types, including pharynx cells, body muscles and coelomocytes. A presumptive null mutation in the T-box factor gene tbx-35, a target of the MED-1 and MED-2 divergent GATA factors, was previously found to result in a profound decrease in the production of MS-derived tissues, although the tbx-35(-) embryonic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.