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Article

Regulation of C. elegans neuronal differentiation by the ZEB-family factor ZAG-1 and the NK-2 homeodomain factor CEH-28.

PloS one - 1 Jan 2014

Ramakrishnan Kalpana, Okkema Peter G

Abstract excerpt

The C. elegans pharyngeal neuron M4 is a multi-functional cell that acts as a cholinergic motor neuron to stimulate peristaltic pharyngeal muscle contraction and as a neuroendocrine cell secreting neuropeptides and growth factors to affect other cells both inside and outside the pharynx. The conserved transcription factors ZAG-1 and CEH-28 are co-expressed in M4 through most of development, and here we examine...

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Identifiers

PMID: 25474681
DOI: 10.1371/journal.pone.0113893
PMCID: PMC4256384

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