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Article

The T-box factor MLS-1 acts as a molecular switch during specification of nonstriated muscle in C. elegans.

Genes & development - 15 Jan 2002

Kostas Stephen A, Fire Andrew

Abstract excerpt

We have isolated mutations in a gene mls-1 that is required for proper specification of nonstriated muscle fates in Caenorhabditis elegans. Loss of MLS-1 activity causes uterine muscle precursors to forego their normal fates, instead differentiating as vulval muscles. We have cloned mls-1 and shown that the product is a member of the T-box family of transcriptional regulators. MLS-1 acts as a cell fate...

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Identifiers

PMID: 11799068
DOI: 10.1101/gad.923102
PMCID: PMC155317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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