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Article

Interpreting a low resolution map of human U1 snRNP using anomalous scatterers.

Structure (London, England : 1993) - 15 Jul 2009

Oubridge Chris, Krummel Daniel A Pomeranz, Leung Adelaine K-W, Li Jade, Nagai Kiyoshi

Abstract excerpt

We recently determined the crystal structure of the functional core of human U1 snRNP, consisting of nine proteins and one RNA, based on a 5.5 A resolution electron density map. At 5-7 A resolution, alpha helices and beta sheets appear as rods and slabs, respectively, hence it is not possible to determine protein fold de novo. Using inverse beam geometry, accurate anomalous signals were obtained from weakly...

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Share to Ribonucleoprotein, U1 Small Nuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19604473
DOI: 10.1016/j.str.2009.05.009
PMCID: PMC2712673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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