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Article

SMN tudor domain structure and its interaction with the Sm proteins.

Nature structural biology - 1 Jan 2001

Selenko P, Sprangers R, Stier G, Bühler D, Fischer U, Sattler M

Abstract excerpt

Spinal muscular atrophy (SMA) is a common motor neuron disease that results from mutations in the Survival of Motor Neuron (SMN) gene. The SMN protein plays a crucial role in the assembly of spliceosomal uridine-rich small nuclear ribonucleoprotein (U snRNP) complexes via binding to the spliceosomal Sm core proteins. SMN contains a central Tudor domain that facilitates the SMN-Sm protein interaction. A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11135666
DOI: 10.1038/83014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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SMN tudor domain structure and its interaction with the Sm proteins.PMID 11135666Read ↗

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Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complexSemantic proximity Read ↗

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