Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

μ-Opioid receptor gene (OPRM1) polymorphism in patients with breast cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2015

Cieślińska Anna, Sienkiewicz-Szłapka Edyta, Kostyra Elżbieta, Fiedorowicz Ewa, Snarska Jadwiga, Wroński Konrad, Tenderenda Michał, Jarmołowska Beata, Matysiewicz Michał

Abstract excerpt

Structure-dependent μ-opioid receptor (MOR) activity is an important element in cancer opioid analgesic effectiveness. It is widely accepted that guanine (G) substitution for adenine (A) at OPRM1 gene sequence position 118 changes receptor glycosylation pattern. This is associated with decreased binding ability in both exogenous and endogenous opioids, resulting in increased human pain resistance. The endogenous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Analgesics, Opioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Gene Frequency

Share to Genetic Association Studies

Share to Receptors, Opioid, mu

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25618602
DOI: 10.1007/s13277-015-3113-z
PMCID: PMC4529459

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

μ-Opioid receptor gene (OPRM1) polymorphism in patients with breast cancer.PMID 25618602Read ↗

Allele frequency and genotype distribution of the opioid receptor μ-1 (OPRM1) A118G polymorphism in the Western Saudi population.Semantic proximity Read ↗

Genotyping the Mu-opioid receptor A118G polymorphism using the real-time amplification refractory mutation system: allele frequency distribution among Brazilians.Semantic proximity Read ↗

Comparison of the Effects of OPRM1 A118G Polymorphism Using Different Opioids: A Prospective Study.Semantic proximity Read ↗

Overview of genetic analysis of human opioid receptors.Semantic proximity Read ↗

Overview of Genetic Analysis of Human Opioid Receptors.Semantic proximity Read ↗

mu-Opioid Receptor Polymorphisms and Breast Cancer Recurrence in Adult Korean Women Undergoing Breast Cancer Surgery: A Retrospective Study.Semantic proximity Read ↗

Consequences of the 118A&gt;G polymorphism in the OPRM1 gene: translation from bench to bedside?Semantic proximity Read ↗

The OPRM1 A118G Polymorphism Revisited: Recent Developments and Implications for Personalized Treatment.Semantic proximity Read ↗

μ-Opioid receptor gene A118G polymorphism predicts survival in patients with breast cancer.Semantic proximity Read ↗

µ-opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain.Semantic proximity Read ↗

Study of the OPRM1 A118G genetic polymorphism associated with postoperative nausea and vomiting induced by fentanyl intravenous analgesia.Semantic proximity Read ↗

Population-specific genetic background for the OPRM1 variant rs1799971 (118A>G): implications for genomic medicine and functional analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.