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Article

Implication of OPRM1 A118G Polymorphism in Opioids Addicts in Pakistan: In vitro and In silico Analysis.

Journal of molecular neuroscience : MN - 1 Aug 2018

Ahmed Madiha, Ul Haq Ihsan, Faisal Muhammad, Waseem Durdana, Taqi Malik Mumtaz

Abstract excerpt

Single nucleotide polymorphism in OPRM1 gene is associated with hedonic and reinforcing consequences of opioids. Risk and protective alleles may vary in different populations. One hundred healthy controls and 100 opioids (predominantly heroin) addicts from Pakistani origin were genotyped for A118G (N40D) polymorphism in OPRM1. Structural and functional impact of the polymorphism on encoded protein was predicted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30033503
DOI: 10.1007/s12031-018-1123-1
PMCID: PMC6132783

Genes

OPRM1
RXRA

Variants

Provenance

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