Article
Two distinct conformations of the conserved RNA-rich decoding center of the small ribosomal subunit are recognized by tRNAs and release factors.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2006
Youngman E M, Cochella L, Brunelle J L, He S, Green R
Abstract excerpt
The mRNA is bound and poised in the decoding center of the small subunit of the ribosome where the genetic code is translated by the tRNAs, which recognize sense codons, and by the release factors, which recognize stop-codons. Structural and biochemical studies have identified key universally conserved nucleotides, G530, A1492, and A1493, that are important for selection of cognate tRNA species during elongation....
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