Article
An analysis of growth, differentiation and apoptosis genes with risk of renal cancer.
PloS one - 24 Mar 2009
Dong Linda M, Brennan Paul, Karami Sara, Hung Rayjean J, Menashe Idan, Berndt Sonja I, Yeager Meredith, Chanock Stephen, Zaridze David, Matveev Vsevolod, Janout Vladimir, Kollarova Hellena, Bencko Vladimir, Schwartz Kendra, Davis Faith, Navratilova Marie, Szeszenia-Dabrowska Neonila, Mates Dana, Colt Joanne S, Holcatova Ivana, Boffetta Paolo, Rothman Nathaniel, Chow Wong-Ho, Rosenberg Philip S, Moore Lee E
Abstract excerpt
We conducted a case-control study of renal cancer (987 cases and 1298 controls) in Central and Eastern Europe and analyzed genomic DNA for 319 tagging single-nucleotide polymorphisms (SNPs) in 21 genes involved in cellular growth, differentiation and apoptosis using an Illumina Oligo Pool All (OPA). A haplotype-based method (sliding window analysis of consecutive SNPs) was used to identify chromosome regions of...
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