Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma.

doi:10.1186/1471-2407-10-196

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Article

Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma.

BMC cancer - 12 May 2010

Tan Min-Han, Wong Chin Fong, Tan Hwei Ling, Yang Ximing J, Ditlev Jonathon, Matsuda Daisuke, Khoo Sok Kean, Sugimura Jun, Fujioka Tomoaki, Furge Kyle A, Kort Eric, Giraud Sophie, Ferlicot Sophie, Vielh Philippe, Amsellem-Ouazana Delphine, Debré Bernard, Flam Thierry, Thiounn Nicolas, Zerbib Marc, Benoît Gérard, Droupy Stéphane, Molinié Vincent, Vieillefond Annick, Tan Puay Hoon, Richard Stéphane, Teh Bin Tean

Abstract excerpt

BACKGROUND: Chromophobe renal cell carcinoma (chRCC) and renal oncocytoma are two distinct but closely related entities with strong morphologic and genetic similarities. While chRCC is a malignant tumor, oncocytoma is usually regarded as a benign entity. The overlapping characteristics are best explained by a common cellular origin, and the biologic differences between chRCC and oncocytoma are therefore of...

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Identifiers

PMID: 20462447
DOI: 10.1186/1471-2407-10-196
PMCID: PMC2883967

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