Article
Molecular inversion probes reveal patterns of 9p21 deletion and copy number aberrations in childhood leukemia.
Cancer genetics and cytogenetics - 1 Aug 2009
Schiffman Joshua D, Wang Yuker, McPherson Lisa A, Welch Katrina, Zhang Nancy, Davis Ronald, Lacayo Norman J, Dahl Gary V, Faham Malek, Ford James M, Ji Hanlee P
Abstract excerpt
Childhood leukemia, which accounts for >30% of newly diagnosed childhood malignancies, is one of the leading causes of death for children with cancer. Genome-wide studies using microarray chips to identify copy number changes in human cancer are becoming more common. In this pilot study, 45 pediatric leukemia samples were analyzed for gene copy aberrations using novel molecular inversion probe (MIP) technology....
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