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Fibroblast Growth Factors in Development and Cancer: Insights from the Mammary and Prostate Glands

1 Jul 2009

Abstract excerpt

The fibroblast growth factor (FGF) family is comprised of 22 ligands that bind and activate several FGF receptor (FGFR) isoforms. Critical roles for FGFs and FGFRs have been well-established during embryonic development. For example, the FGF10/FGFR2IIIb axis has been linked to embryonic development of both the mammary and prostate glands, which are the subject of this review. Furthermore, recent studies using...

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PMID: 19601767
DOI: 10.2174/138945009788680419

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