Article
TLR-2 Arg753Gln, TLR-4 Asp299Gly, and TLR-4 Thr399Ile polymorphisms in Henoch Schonlein purpura with and without renal involvement.
Rheumatology international - 1 Mar 2010
Soylu Alper, Kizildağ Sefa, Kavukçu Salih, Cingöz Sultan, Türkmen Mehmet, Demir Belde Kasap, Sakizli Meral
Abstract excerpt
Infections may trigger or aggravate glomerulonephritidis and renal vasculitis like Henoch Schonlein purpura (HSP). HSP is seen more frequently in patients with familial Mediterranean fever in which TLR-2 Arg753Gln polymorphism frequency is increased. Although renal involvement is the most important factor affecting the prognosis in HSP, it is not known which patients will have renal disease or why some patients...
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