Article
Functional variants in intercellular adhesion molecule-1 and toll-like receptor-4 genes are more frequent in children with febrile urinary tract infection with renal parenchymal involvement.
Acta paediatrica (Oslo, Norway : 1992) - 1 Feb 2018
Hussein Almontaser, Saad Khaled, Askar Eman, Zahran Asmaa M, Farghaly Hekma, Metwalley Kotb, Elderwy Ahmad A
Abstract excerpt
AIM: We studied the functional polymorphisms of intercellular adhesion molecule-1 (ICAM-1) and toll-like receptor-4 (TLR-4) genes and risk of acute pyelonephritis (APN) in children attending Assiut University Children's Hospitals, Egypt, from 2011 to 2015. METHODS: Urinary tract infections (UTIs) were diagnosed in 380 children: 98 had APN and 282 had lower UTIs. Four single-nucleotide polymorphisms in ICAM-1 and...
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