Article
Association of TLR9 gene polymorphisms with lupus nephritis in a Chinese Han population.
Clinical and experimental rheumatology - 1 Jan 2000
Zhou Xu-Jie, Lv Ji-Cheng, Cheng Wen-Rong, Yu Lei, Zhao Ming-Hui, Zhang Hong
Abstract excerpt
OBJECTIVES: Although increasing data have supported the possible role of TLR-9 in the pathogenesis of lupus nephritis (LN), the effect of TLR-9 on the lupus phenotype remains controversial. The aim of this study was to associate common variants in the TLR9 gene with susceptibility to lupus nephritis in the Chinese population to further ascertain whether it is a susceptible locus for SLE, especially its likely...
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