Article
Inducible nitric oxide synthase gene polymorphisms are associated with a risk of nephritis in Henoch-Schönlein purpura children.
European journal of pediatrics - 1 Aug 2017
Jiang Jue, Duan Wuqiong, Shang Xu, Wang Hua, Gao Ya, Tian Peijun, Zhou Qi
Abstract excerpt
Henoch-Schönlein purpura (HSP) is the most common form of systemic small-vessel vasculitis in children, and HSP nephritis (HSPN) is a major complication of HSP and is the primary cause of morbidity and mortality. Previous studies have suggested that inducible nitric oxide synthase (iNOS) may play an important role in the pathogenesis of HSP. In this study, we performed a detailed analysis to investigate the...
Topics
- Asian People
- Case-Control Studies
- Child
- China
- Female
- Follow-Up Studies
- Gene Frequency
- Genetic Markers
- Genetic Predisposition to Disease
- Genotype
- Humans
- IgA Vasculitis
- Male
- Nephritis
- Nitric Oxide Synthase Type II
- Polymorphism, Single Nucleotide
- Risk Factors