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Article

Association of TLR4 gene polymorphisms with childhood Henoch-Schönlein purpura in a Chinese population.

Rheumatology international - 1 Nov 2017

Xu Hui, Jiang Guizhen, Shen Hongqiang, Li Wei, Mao Jianhua, Pan Yanxiang

Abstract excerpt

Recent studies demonstrated that aberrant activation of Toll-like receptor (TLR) 4 was involved in the pathogenesis of Henoch-Schönlein purpura (HSP). In this study, we evaluated the association between TLR4 gene polymorphisms and the risk of childhood HSP in a Chinese population. A total of 175 HSP patients and 186 controls were recruited in this case-control study. Three single-nucleotide polymorphisms of the...

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Source

Identifiers

PMID: 28905155
DOI: 10.1007/s00296-017-3815-1

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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