Article
Relevant genetic polymorphisms and kidney expression of Toll-like receptor (TLR)-5 and TLR-9 in lupus nephritis.
Clinical and experimental immunology - 1 Dec 2017
Elloumi N, Fakhfakh R, Abida O, Ayadi L, Marzouk S, Hachicha H, Fourati M, Bahloul Z, Mhiri M N, Kammoun K, Masmoudi H
Abstract excerpt
Toll-like receptor (TLR) genetic polymorphisms may modify their expression causing inflammatory disorders and influencing both susceptibility and severity of lupus erythematosus. We aim to determine whether TLR-5 and TLR-9 gene polymorphisms are implicated in the susceptibility to systemic lupus erythematosus (SLE) and lupus nephritis (LN) and to evaluate their expressions and distributions in renal LN patients'...
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