Article
Heart development in normal and cardiac-lethal mutant axolotls: a model for the control of vertebrate cardiogenesis.
Differentiation; research in biological diversity - 1 Aug 1991
Smith S C, Armstrong J B
Abstract excerpt
The mechanisms which regulate myocardial differentiation are poorly understood. The cardiac-lethal (c) mutant of Ambystoma mexicanum, in which the heart never begins to beat, provides a valuable model system for studying this process. Using an in vitro assay, we examine the nature of the defect in c/c embryos and find (contrary to previous reports) that the inductive endoderm is not affected by the mutation....
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