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Article

Differential APP gene expression in rat cerebral cortex, meninges, and primary astroglial, microglial and neuronal cultures

4 Nov 1991

Abstract excerpt

Differential amyloid precursor protein (APP) gene expression was investigated in primary cultures of astrocytes, neurons and microglia from neonatal rat cerebral cortex as well as in meninges, and young and adult cerebral cortex tissues in order to define the possible contribution of individual CNS cell types in beta AP deposition. Meninges and neurons contained higher levels of total APP mRNA than glial cells...

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PMID: 1959603
DOI: 10.1016/0014-5793(91)80861-v

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