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Article

Quantification of APP and APLP2 mRNA in APOE genotyped Alzheimer's disease brains.

Brain research. Molecular brain research - 31 Dec 1996

Johnston J A, Norgren S, Ravid R, Wasco W, Winblad B, Lannfelt L, Cowburn R F

Abstract excerpt

Amyloid precursor protein (APP) is metabolised to produce A beta, a peptide found aggregated in Alzheimer's disease neuritic plaques. APP is a member of a multigene protein family which includes amyloid precursor-like protein 2 (APLP2). Since A beta accumulation can be triggered by factors acting up- or downstream of APP processing, we investigated whether APP mRNA expression was altered in Alzheimer's disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9037522
DOI: 10.1016/s0169-328x(96)00161-1

Genes

APP
APLP2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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