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Article

The combined effect of the T2DM susceptibility genes is an important risk factor for T2DM in non-obese Japanese: a population based case-control study.

BMC medical genetics - 24 Feb 2012

Yamakawa-Kobayashi Kimiko, Natsume Maki, Aoki Shingo, Nakano Sachi, Inamori Tomoko, Kasezawa Nobuhiko, Goda Toshinao

Abstract excerpt

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a complex endocrine and metabolic disorder. Recently, several genome-wide association studies (GWAS) have identified many novel susceptibility loci for T2DM, and indicated that there are common genetic causes contributing to the susceptibility to T2DM in multiple populations worldwide. In addition, clinical and epidemiological studies have indicated that obesity is a...

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PMID: 22364391
DOI: 10.1186/1471-2350-13-11
PMCID: PMC3313886

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