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Article

The gene-gene interaction of INSIG-SCAP-SREBP pathway on the risk of obesity in Chinese children.

BioMed research international - 1 Jan 2014

Liu Fang-Hong, Song Jie-Yun, Shang Xiao-Rui, Meng Xiang-Rui, Ma Jun, Wang Hai-Jun

Abstract excerpt

BACKGROUND: Childhood obesity has become a global public health problem in recent years. This study aimed to explore the association of genetic variants in INSIG-SCAP-SREBP pathway with obesity in Chinese children. METHODS: A case-control study was conducted, including 705 obese cases and 1,325 nonobese controls. We genotyped 15 single nucleotide polymorphisms (SNPs) of five genes in INSIG-SCAP-SREBP pathway,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25028659
DOI: 10.1155/2014/538564
PMCID: PMC4083216

Genes

SCAP
INSIG2
INSIG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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