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Article

Evaluation of the ENPP1 and PLIN single nucleotide polymorphisms with type 2 diabetes in a Taiwanese population: evidence for replication and gene-gene interaction.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Dec 2012

Wang Chun-Hsiang, Ke Wan-Sheng, Lin Eugene

Abstract excerpt

BACKGROUND: Addressing gene-gene interactions is essential in defining a trait implicating complex disease-related mechanisms. In this study, we aimed to explore both main effects of single-locus and multi-locus interactions to test the hypothesis that the ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) and perilipin (PLIN) genes may contribute to the etiology of type 2 diabetes (T2D) independently...

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Source

Identifiers

PMID: 23111648
DOI: 10.2310/JIM.0b013e3182746498

Genes

ENPP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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