Article
Multilocus analyses of seven candidate genes suggest interacting pathways for obesity-related traits in Brazilian populations.
Obesity (Silver Spring, Md.) - 1 Jun 2011
Angeli Cláudia B, Kimura Lilian, Auricchio Maria T, Vicente João P, Mattevi Vanessa S, Zembrzuski Verônica M, Hutz Mara H, Pereira Alexandre C, Pereira Tiago V, Mingroni-Netto Regina C
Abstract excerpt
We investigated whether variants in major candidate genes for food intake and body weight regulation contribute to obesity-related traits under a multilocus perspective. We studied 375 Brazilian subjects from partially isolated African-derived populations (quilombos). Seven variants displaying conflicting results in previous reports and supposedly implicated in the susceptibility of obesity-related phenotypes...
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