Article
Association analyses suggest multiple interaction effects of the methylenetetrahydrofolate reductase polymorphisms on timing of menarche and natural menopause in white women.
Menopause (New York, N.Y.) - 1 Jan 2000
Liu Pengyuan, Lu Yan, Recker Robert R, Deng Hong-Wen, Dvornyk Volodymyr
Abstract excerpt
OBJECTIVE: This study aimed to investigate whether polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene are associated with age at menarche and age at natural menopause in white women. METHODS: In a cross-sectional study, a total of 305 randomly selected unrelated white women were genotyped for six single nucleotide polymorphisms (SNPs) of the MTHFR gene (including one common replacement,...
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