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Article

TNFRSF11A and TNFSF11 are associated with age at menarche and natural menopause in white women.

Menopause (New York, N.Y.) - 1 Jan 2000

Lu Yan, Liu Pengyuan, Recker Robert R, Deng Hong-Wen, Dvornyk Volodymyr

Abstract excerpt

OBJECTIVE: Menarche and menopause mark the lower and upper limits of the female reproductive period. The timing of these events influences women's health in later life. The onsets of menarche and menopause have a strong genetic basis. We tested two genes, TNFRSF11A (RANK) and TNFSF11 (RANKL), for their association with age at menarche (AM) and age at natural menopause (ANM). METHODS: Nineteen single nucleotide...

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Source

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Identifiers

PMID: 20531232
DOI: 10.1097/gme.0b013e3181d5d523
PMCID: PMC2939156

Genes

TNFSF11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Research trail→

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TNFRSF11A and TNFSF11 are associated with age at menarche and natural menopause in white women.PMID 20531232Read ↗

Gene polymorphisms in RANKL/RANK/OPG pathway are associated with ages at menarche and natural menopause in Chinese women.Semantic proximity Read ↗

Polymorphisms of the TNF, LTA, and TNFRSF1B genes are associated with onsets of menarche and menopause in US women of European ancestry.Semantic proximity Read ↗

Association analyses suggest the effects of RANK and RANKL on age at menarche in Chinese women.Semantic proximity Read ↗

ALOX12 gene is associated with the onset of natural menopause in white women.Semantic proximity Read ↗

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Polymorphisms in genes in the RANKL/RANK/OPG pathway are associated with bone mineral density at different skeletal sites in post-menopausal women.Semantic proximity Read ↗

Genome-wide association studies and epistasis analyses of candidate genes related to age at menarche and age at natural menopause in a Korean population.Semantic proximity Read ↗

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