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Article

Age at menarche and menopause is not associated with two common genetic variants in the methylenetetrahydrofolate reductase (MTHFR) gene.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception - 1 Aug 2011

Cerne Jasmina-Ziva, Pohar-Perme Maja, Cerkovnik Petra, Gersak Ksenija, Novakovic Srdjan

Abstract excerpt

OBJECTIVES: The study aimed at investigating the independent and the combined effects of the two common genetic variants in the methylenetetrahydrofolate reductase (MTHFR) gene, 677C > T and 1298A > C, and their interaction with lifestyle factors on timing of menarche and natural menopause. METHODS: Postmenopausal women (N = 792) were assessed for the association of the two genetic variants with age at menarche...

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Identifiers

PMID: 21506883
DOI: 10.3109/13625187.2011.575481

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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