Article
Killer cell immunoglobulin-like receptor allele discrimination by high-resolution melting.
Human immunology - 1 Oct 2009
Gonzalez Asensio, McErlean Colum, Meenagh Ashley, Shovlin Tanya, Middleton Derek
Abstract excerpt
New molecular techniques for allele discrimination such as high-resolution melting (HRM) allow fast, reliable and high-throughput typing without the use of oligonucleotide probes. HRM can also provide an alternative for problematic allele assignments caused by the presence of homopolymeric regions or ambiguous haplotyping. We show here how we have used HRM to introduce upgrades in our KIR allele level typing...
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