Article
An Improved Method With High Specificity for KIR2DL1 Functional Allele Typing.
Laboratory medicine - 1 Jan 2015
Bari Rafijul, Schell Sarah, Tuggle MaCal, Leung Wing
Abstract excerpt
As new killer-cell immunoglobulin-like receptor (KIR) alleles are discovered, a challenge in KIR typing is maintaining sensitivity and specificity. A single nucleotide polymorphism assay can be used to type functional KIR2DL1 alleles. We improved recently on the earlier method by using a higher-specificity assay. The major modifications include the development of sequence-specific primers to selectively amplify...
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