Article
Failure of spinal cord oligodendrocyte development in mice lacking neuregulin.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jan 1999
Vartanian T, Fischbach G, Miller R
Abstract excerpt
Oligodendrocytes develop from a subpopulation of precursor cells within the ventral ventricular zone of the spinal cord. The molecular cues that direct this spatially and temporally restricted event seem to originate in part from structures ventral to and within the spinal cord. Here, we present...
Topics
- Animals
- Embryonic and Fetal Development
- Genotype
- Glycoproteins
- Immunohistochemistry
- Mice
- Mice, Knockout
- Microscopy, Fluorescence
- Nerve Tissue Proteins
- Neuregulins
- Oligodendroglia
- Organ Culture Techniques
- Recombinant Proteins
- Spinal Cord