Article
The right to choose: multiple pathways for activating copper,zinc superoxide dismutase.
The Journal of biological chemistry - 11 Sept 2009
Leitch Jeffry M, Yick Priscilla J, Culotta Valeria C
Abstract excerpt
Since the discovery of SOD1 in 1969, there have been numerous achievements made in our understanding of the enzyme's biochemical reactivity and its role in oxidative stress protection and as a genetic determinant in amyotrophic lateral sclerosis. Many recent advances have also been made in understanding the "activation" of SOD1, i.e. the process by which an inert polypeptide is converted to a mature active enzyme...
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