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Article

SOD1 Function and Its Implications for Amyotrophic Lateral Sclerosis Pathology: New and Renascent Themes.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry - 1 Oct 2015

Bunton-Stasyshyn Rosie K A, Saccon Rachele A, Fratta Pietro, Fisher Elizabeth M C

Abstract excerpt

The canonical role of superoxide dismutase 1 (SOD1) is as an antioxidant enzyme protecting the cell from reactive oxygen species toxicity. SOD1 was also the first gene in which mutations were found to be causative for the neurodegenerative disease amyotrophic lateral sclerosis (ALS), more than 20 years ago. ALS is a relentless and incurable mid-life onset disease, which starts with a progressive paralysis and...

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PMID: 25492944
DOI: 10.1177/1073858414561795

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SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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