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Article

Genetic variants associated with deep vein thrombosis: the F11 locus.

Journal of thrombosis and haemostasis : JTH - 1 Nov 2009

Li Y, Bezemer I D, Rowland C M, Tong C H, Arellano A R, Catanese J J, Devlin J J, Reitsma P H, Bare L A, Rosendaal F R

Abstract excerpt

BACKGROUND: Recent studies have found associations between deep vein thrombosis (DVT) and single nucleotide polymorphisms (SNPs) in a 4q35.2 locus that contains genes encoding factor XI (F11), a cytochrome P450 family member (CYP4V2), and prekallikrein (KLKB1). OBJECTIVE: We investigated which of the common SNPs in this locus are independently associated with DVT. METHODS: The study populations were the Leiden...

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Source

Identifiers

PMID: 19583818
DOI: 10.1111/j.1538-7836.2009.03544.x

Genes

KLKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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