Article
Is there still room for additional common susceptibility alleles for venous thromboembolism?
Journal of thrombosis and haemostasis : JTH - 1 Sept 2016
Trégouët D A, Delluc A, Roche A, Derbois C, Olaso R, Germain M, de Andrade M, Tang W, Chasman D I, van Hylckama Vlieg A, Reitsma P H, Kabrhel C, Smith N, Morange P E
Abstract excerpt
UNLABELLED: Essentials Genetic architecture of venous thromboembolism (VTE) remains to be fully disentangled. 11 newly discovered candidate polymorphisms were genotyped in 3019 VTE cases and 2605 controls. None of the 11 polymorphisms were significantly associated with VTE risk. Additional major efforts are needed to identify VTE-associated genetic variants. SUMMARY: Background Through a meta-analysis of 12...
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