Article
Gene variants associated with deep vein thrombosis.
JAMA - 19 Mar 2008
Bezemer Irene D, Bare Lance A, Doggen Carine J M, Arellano Andre R, Tong Carmen, Rowland Charles M, Catanese Joseph, Young Bradford A, Reitsma Pieter H, Devlin James J, Rosendaal Frits R
Abstract excerpt
CONTEXT: The genetic causes of deep vein thrombosis (DVT) are not fully understood. OBJECTIVE: To identify single-nucleotide polymorphisms (SNPs) associated with DVT. DESIGN, SETTING, AND PATIENTS: We used 3 case-control studies of first DVT. A total of 19 682 gene-centric SNPs were genotyped in 443 cases and 453 controls from the Leiden Thrombophilia Study (LETS, 1988-1992). Twelve hundred six SNPs associated...
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