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Article

Tyrosine phosphorylation of vinexin in v-Src-transformed cells attenuates the affinity for vinculin.

Biochemical and biophysical research communications - 11 Sept 2009

Umemoto Tsutomu, Tanaka Kana, Ueda Kazumitsu, Kioka Noriyuki

Abstract excerpt

Vinexin is an adaptor-type focal adhesion protein that interacts with vinculin. Here, we report the tyrosine phosphorylation of vinexin alpha in v-Src-transformed NIH3T3 cells. Point mutational analysis of vinexin alpha clarified that three tyrosine residues in vinexin alpha were phosphorylated. A non-phosphorylatable mutant of vinexin alpha had higher binding affinity for vinculin than its wild-type counterpart....

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Source

Identifiers

PMID: 19580787
DOI: 10.1016/j.bbrc.2009.07.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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