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Article

Mouse carnitine-acylcarnitine translocase (CACT) is transcriptionally regulated by PPARalpha and PPARdelta in liver cells.

Biochimica et biophysica acta - 1 Oct 2009

Gutgesell Anke, Wen Gaiping, König Bettina, Koch Alexander, Spielmann Julia, Stangl Gabriele I, Eder Klaus, Ringseis Robert

Abstract excerpt

BACKGROUND: Hepatic PPARalpha acts as the primary mediator of the adaptive response to fasting by upregulation of a number of genes involved in fatty acid catabolism. Whether carnitine-acylcarnitine translocase (CACT), which mediates the import of acylcarnitines into the mitochondrial matrix for subsequent beta-oxidation of fatty acid moieties, is also regulated by PPARalpha in the liver has not yet been...

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PMID: 19577614
DOI: 10.1016/j.bbagen.2009.06.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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