Article
Nutritional regulation and role of peroxisome proliferator-activated receptor delta in fatty acid catabolism in skeletal muscle.
Biochimica et biophysica acta - 4 Jul 2003
Holst Dorte, Luquet Serge, Nogueira Véronique, Kristiansen Karsten, Leverve Xavier, Grimaldi Paul A
Abstract excerpt
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors primarily involved in lipid homeostasis. PPARdelta displays strong expression in tissues with high lipid metabolism, such as adipose, intestine and muscle. Its role in skeletal muscle remains largely unknown. After a 24-h starvation period, PPARdelta mRNA levels are dramatically up-regulated in gastrocnemius muscle of mice and restored to...
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