Article
Rho1 has multiple functions in Drosophila wing planar polarity.
Developmental biology - 1 Sept 2009
Yan Jie, Lu Qiuheng, Fang Xiaolan, Adler Paul N
Abstract excerpt
The frizzled (fz) signaling/signal transduction pathway controls planar cell polarity in both vertebrates and invertebrates. Previous data implicated Rho1 as a component of the fz pathway in Drosophila but it was unclear how it functioned. The existence of a G Protein Binding-Formin Homology 3 (GBD-FH3) domain in Multiple Wing Hairs, a downstream component of the pathway suggested that Rho1 might function by...
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