Article
Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development.
Development (Cambridge, England) - 1 Dec 1999
Magie C R, Meyer M R, Gorsuch M S, Parkhurst S M
Abstract excerpt
Rho GTPases play an important role in diverse biological processes such as actin cytoskeleton organization, gene transcription, cell cycle progression and adhesion. They are required during early Drosophila development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. We isolated loss-of-function mutations in the...
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