Article
Combover/CG10732, a novel PCP effector for Drosophila wing hair formation.
PloS one - 1 Jan 2014
Fagan Jeremy K, Dollar Gretchen, Lu Qiuheng, Barnett Austen, Pechuan Jorge Joaquin, Schlosser Andreas, Pfleger Cathie, Adler Paul, Jenny Andreas
Abstract excerpt
The polarization of cells is essential for the proper functioning of most organs. Planar Cell Polarity (PCP), the polarization within the plane of an epithelium, is perpendicular to apical-basal polarity and established by the non-canonical Wnt/Fz-PCP signaling pathway. Within each tissue, downstream PCP effectors link the signal to tissue specific readouts such as stereocilia orientation in the inner ear and...
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