Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mtl interacts with members of Egfr signaling and cell adhesion genes in the Drosophila eye.

Fly - 1 Jan 2000

Muñoz-Soriano Verónica, Belacortu Yaiza, Durupt Fabrice C, Muñoz-Descalzo Silvia, Paricio Nuria

Abstract excerpt

Mtl is a member of the Rho family of small GTPases in Drosophila. It was shown that Mtl is involved in planar cell polarity (PCP) establishment, together with other members of the same family like Cdc42, Rac1, Rac2 and RhoA. However, while Rac1, Rac2 and RhoA function downstream of Dsh in Fz/PCP signaling and upstream of a JNK cassette, Mtl and Cdc42 do not. To determine the functional context of Mtl during PCP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion
Share to Cell Polarity
Share to Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to ErbB Receptors

Share to Phenotype

Share to rho GTP-Binding Proteins

Share to Signal Transduction

Source

Identifiers

PMID: 21441778
DOI: 10.4161/fly.5.2.15457

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mtl interacts with members of Egfr signaling and cell adhesion genes in the Drosophila eye.PMID 21441778Read ↗

Analysis of the role of the Rac/Cdc42 GTPases during planar cell polarity generation in Drosophila.Semantic proximity Read ↗

Rho1 has multiple functions in Drosophila wing planar polarity.Semantic proximity Read ↗

EGF signaling and ommatidial rotation in the Drosophila eye.Semantic proximity Read ↗

The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye.Semantic proximity Read ↗

Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development.Semantic proximity Read ↗

Distinct developmental roles for direct and indirect talin-mediated linkage to actin.Semantic proximity Read ↗

Role of Rho-family proteins in cell adhesion and cancer.Semantic proximity Read ↗

The role of RhoA in tissue polarity and Frizzled signalling.Semantic proximity Read ↗

Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons.Semantic proximity Read ↗

The actin binding sites of talin have both distinct and complementary roles in cell-ECM adhesion.Semantic proximity Read ↗

Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling.Semantic proximity Read ↗

Rho-kinase regulates tissue morphogenesis via non-muscle myosin and LIM-kinase during Drosophila development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.